The 42nd Ward is where business happens in Chicago. Downtown Chicago's 42nd Ward is the city’s Central Business District, including the Gold Coast, River North, Streeterville, New East Side, Near West Loop, Fulton River District and Loop neighborhoods. The 42nd Ward is Chicago's economic engine and the hub of our hospitality and tourism industries. The 42nd Ward is home to Chicago's Fortune 100 headquarters; major law & financial firms; hundreds of major retailers; and many thousands of small to medium-sized locally-owned businesses.